Wilms’ Tumour Symptoms

3791 - Gene ResultKDR kinase insert domain receptor [ (human)]

Updated: 3 days ago
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase.


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Wilms tumour (nephroblastoma) | Children's cancers | Cancer Research UK

Updated: 3 days ago
Wilms tumour (nephroblastoma) is a type of kidney cancer found in children. Find out about how it is diagnosed and treated, and resources and organisations that can help you to cope.


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What is the life expectancy of someone with Wilms tumor?

For Wilms tumors, survival is often measured using a 4-year survival rate. This refers to the percentage of children who live at least 4 years after their cancer is diagnosed. For example, a 4-year survival rate of 80% means that an estimated 80 out of 100 children who have that cancer are still alive 4 years after being diagnosed.

What is Wilms tumor and how is it treated?

Treatment for Wilms' tumor usually involves surgery and chemotherapy, and sometimes radiation therapy. Treatments may vary by the stage of the cancer. Because this type of cancer is rare, your child's doctor may recommend that you seek treatment at a children's cancer center that has experience treating this type of cancer.

What causes Wilms tumor?

Wilms' tumor has many causes, which can broadly be categorized as syndromic and non-syndromic. Syndromic causes of Wilms' tumor occur as a result of alterations to genes such as the Wilms Tumor 1 (WT1) or Wilms Tumor 2 (WT2) genes, and the tumor presents with a group of other signs and symptoms.

What is survival rate of Wilms tumor?

The 5-year survival rate for children with Wilms tumor is 93%. However, the rate varies according to the stage of the disease. Stage I, II, and III tumors with a favorable histology have a 4-year survival rate that ranges from 95% to 100%.

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